Articles

Vol. 6 No. 4 (2026): PTNM 2026 Fourth Issue

Published: 2026-07-07

Neuroprotective Effect of Jobelyn® on Ketamine-Induced Schizophrenia-Like Behaviors and Oxidative Damage in Mice Brain

Itivere A Omogbiya, Benneth Ben-Azu, Maxwell Oboh, Oruese Orovwigho, Tarela M E Daubry, Solomon Umukoro

1-14 https://doi.org/10.52406/ptnm.v6i4.176

Multiple Targets of Polyphenols from Picralima nitida on Blood Glucose Regulatory Enzymes

Emmanuel Eimiomodebheki Odion, Paul Ejime Elede, Kingsley Peter Akpeh, Adaeze Phina Uchendu, Theresa Chioma Umeji

15-31 https://doi.org/10.52406/ptnm.v6i4.178

Vol. 6 No. 2-3 (2026): PTNM 2026 Second & Third Issue

Published: 2026-05-09

Efficacy and Mechanisms of Tribulus terrestris in the Management of Erectile Dysfunction: A Systematic Review of Preclinical Studies

Walter C Enemuo, Victor O Okwor, Cynthia C Agbo, Bernard O Mmadubike, Chinonyelum E. Agbo, Ezinwanne J Ugochukwu, AbdulMuminu Isah, Chukwuemeka S Nworu

1-19 https://doi.org/10.52406/ptnm.v6i2-3.166

Modulatory Effects of Ethanol Root Extract of Mucuna pruriens (EREMP) on Lead-Induced Hepatic Injury: Biochemical and Histological Evidence

Vivian O Ojiakor, Ayugha A Nsan, Benneth Ben-Azu

20-30 https://doi.org/10.52406/ptnm.v6i2-3.174

Vol. 6 No. 1 (2026): PTNM 2026 First Issue

Published: 2026-01-13

Doxorubicin-induced Hepatorenal Dysfunctions in Wistar rats: Mechanistic Protective Role of Diosmin-Hesperidin Fixed-Dose Combinations Mediated via Oxidative and Inflammatory Stress Suppression

Adejuwon A Adeneye, Kehinde S Fashikun, Nadrah G Akinlade, Abdulfatai O Ojewale, Ikechuckwu I Okoye

1-14 https://doi.org/10.52406/ptnm.v6i1.141

Comparing Three Extractive Solvents for Phytochemicals in Citrullus colocynth Relevant for Polycystic Ovarian

Airat A Bakare, Fatimoh O Adeoye, Abraham A Osinubi, Comfort Bamikefa

15-21 https://doi.org/10.52406/ptnm.v6i1.128

Vol. 5 No. 5-6 (2025): PTNM 2025 Fifth & Sixth Issue

Published: 2025-12-03

Evaluation of the Adsorptive Capacity of some Activated Plant Materials on Cyanide: An In vitro Study

Casimir C Ofor, Godwin C Akuodor, Emmanuel S Nwodo, Kenneth A Nwankwo, David H Nweke, John I Idume

1-7 https://doi.org/10.52406/ptnm.v5i5-6.115

Vitamin D and Calcium Homeostasis in Bone Health Among Individuals with Disorders of Sex Development: A Review

Kasimu Saidu, Bello Lawal Danchadi

8-16 https://doi.org/10.52406/ptnm.v5i5-6.129

Vol. 5 No. 3-4 (2025): PTNM 2025 Third & Fourth Issue

Published: 2025-09-01

Evaluation the Aqueous Leaf Extract and Solvent Fractions of Pyrenacantha staudtii Engl. (Icancinaceae) for Antidepressant and Anxiolytic-like Activities in Mice

Olayemi K Wakeel, Damola O Komolafe, Mathew K Bello, Ayodeji F Ajayi

1-8 https://doi.org/10.52406/ptnm.v5i3-4.110

Ameliorative Effects of Honey on Petrol Vapor-Induced Oxidative Stress in the Reproductive System of Female Wistar Rats

Ridwanu Z Abubakar, Shaibu O Bello, Aminu Chika, Mohammed Umar, Murtala B Abubakar

9-18 https://doi.org/10.52406/ptnm.v5i3-4.113

Methanol Leaf Extract of Andrographis paniculata Reverses Behavioral and Neuro-biochemical Changes Induced by Chronic Restraint Stress in Mice

Joseph A Badejo, Olasubomi F Sotunde, Mary O Ologe, Obaro S Michael, Babatunde A Alabi, Emmanuel B Ileri-Oluwa, Ezekiel O Iwalewa

19-28 https://doi.org/10.52406/ptnm.v5i3-4.116

Protective Effect of Pleurotus tuberregium Polysaccharide (PTP) and Ganoderma lucidum Polysaccharide (GLP) on Lead-Induced Testicular Derangement in Rats

Michael Oluwatosin Sobowale, Olufunke Esan Olorundare, Saheed Olanrewaju Afolabi, Abayomi Mayowa Ajayi, Jarikre Theophilus Aghogho

29-39 https://doi.org/10.52406/ptnm.v5i3-4.118

Evaluation of the Hepato-Pancreatic Toxicities of Selected Antibiotics in Male Wistar Rats

Ibrahim K Ibrahim, Adams Olalekan Omoaghe, Yusuf Hussaini Mailabari, Tony Ezike, Nnamdi Ejieh, Samuel Kehinde Olaniyi

40-52 https://doi.org/10.52406/ptnm.v5i3-4.96

Ameliorative Effects of Pumpkin Seed Oil on Sexual-Reproductive Indices of Salt-loaded Male Rats: Involvement of the Hypothalamic-Pituitary-Gonadal Axis

Toheeb A Ajibola, Linus A Enye, Mujeeb A Adedokun, Olusola S Saka, Seun O Ayegbusi, Olabisi I Abolaji, Edem E Edem

53-66 https://doi.org/10.52406/ptnm.v5i3-4.119

Vol. 5 No. 1-2 (2025): PTNM 2025 First & Second Issue

Published: 2025-06-01

Uncovering Drugs with Anti-Tubercular Activity: A Computer-Aided Drug Discovery Approach

Abdulmajeed Yunusa, Peter James, Albashir Tahir

1-8 https://doi.org/10.52406/ptnm.v5i1-2.100

Evaluation of the Antisickling Property of a Hydro-Alcohol Root Extract of Rauwolfia vomitoria Afzel (Apocynaceae)

Valentine O Adegoke, Oluwakanyinsola A Salawu, Dickson O Uwaya, Raymond I Ozolua

9-19 https://doi.org/10.52406/ptnm.v5i1-2.102

Elucidation of the Possible Mechanism of Antinociceptive Action of Methanol Stem Bark Extract of Zanthoxylum gilletii (De Wild.) in Mice

Saidi Odoma, Gilbert Bwire

20-24 https://doi.org/10.52406/ptnm.v5i1-2.104

Prediction of Antimalarial Target Proteins in Plasmodium falciparum Using Network Pharmacology Approach

Omobhude Fidelis Aluefua, Muhammad Umar Tukur

25-30 https://doi.org/10.52406/ptnm.v5i1-2.101

Ameliorative Effects of Ganoderma lucidum on Pb-induced Toxicity in Wistar Rats

Michael T. Sobowale, John. A. Saliu

31-40 https://doi.org/10.52406/ptnm.v5i1-2.106

Vol. 4 No. 3-4 (2024): PTNM 2024 Third & Fourth Issue

Published: 2024-12-01

Protective Antiulcer Property of Ricinodendron heudelotii (Euphorbiaceae) Seed Oil and Its GC/MS Profile

Kenneth O. Okolo, Njideka I. Ani, Raymond O. Offiah

1-11 https://doi.org/10.52406/ptnm.v4i3-4.94

Vol. 4 No. 1-2 (2024): PTNM 2024 First & Second Issue

Published: 2024-06-01

Protective Effects of Aqueous-Ethanol Leaf Extract of Justicia Carnea Lindl. and Silymarin on Thioacetamide-Induced Hepatorenal Injury in Rats

SHIRLEY ONAGBONFEOANA EBHOHON, EKENE VICTOR ASOYA, MARK KALU, ONYEKA LOVETH UGOCHUKWU, AMARACHI JOY INYAMA

1-9 https://doi.org/10.52406/ptnm.v4i1-2.87

Vol. 3 No. 3-4 (2023): PTNM 2023 Third & Fourth Issue

Published: 2023-12-01

OPTIMIZATION OF CULTURE CONDITIONS AND PARTIAL PURIFICATION OF PHYTASE ENZYME ISOLATED FROM BACTERIAL ISOLATES

Chinedu G Ohaegbu, Ome K Achi, Ejikeme Nwachukwu, Anayochukwu C Ngene, Ngozi K Achi

1-11 https://doi.org/10.52406/ptnm.v3i3-4.63

Vol. 3 No. 2 (2023): PTNM 2023 Second Issue

Published: 2023-06-01

GC/MS Analysis and a 30-day Toxicological Evaluation of a Nigerian Immunomodulatory Polyherbal Supplement (PHS)

Saheed O Afolabi, Olufunke Olorundare, Olatunde B Akanbi, Matthew K Bello, Anoka Njan, Olalekan A Agede, Jeptha Oche, Akinleye O Akinsola, Mary Ologe, Samuel Ibiyemi

1-14 https://doi.org/10.52406/ptnm.v3i2.70

NUTRITIONAL, ELEMENTAL, AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF HONEY SAMPLES FROM SELECTED APIARIES IN EDO AND OSUN STATE

Rosephine Enadeghe, Eugene O Odoh

15-22 https://doi.org/10.52406/ptnm.v3i2.65

Vol. 3 No. 1 (2023): PTNM 2023 First Issue

Published: 2023-03-01

Atomic Absorption Spectroscopic (AAS) Analysis of Heavy Metals and Health Risks Assessment of some Common Energy Drinks

Samuel J. Bunu, Benjamin U. Ebeshi, Hilda F. Kpun, Adesegun J. Kashimawo, Edebi N. Vaikosen, Chubiyojo B. Itodo

1-10 https://doi.org/10.52406/ptnm.v1i1.55

Acute and Reproductive Toxicity of Freeze-dried and Steam-dried Extracts of Tradomal® in Drosophila melanogaster

Maryam Adenike Salaudeen, Salamatu Onini Sadiq, Mohammad Garba Magaji

11-15 https://doi.org/10.52406/ptnm.v3i1.67

Vol. 2 No. 4-6 (2022): PTNM 2022 Fourth - Sixth Issue

Published: 2023-02-06

Evaluation of the Antitussive and Analgesic Activities of Peperomia pellucida Whole Plant Methanol Extract in Rodents

Dickson O. Uwaya, Faith O. Ikuoyemwen, Oscar N. Aghedo

1-8 https://doi.org/10.52406/ptnm.v2i4-6.47

Evaluation of in vitro Antioxidant Properties of Methanol Extract and Fractions of Cola rostrata (K. Schum) Leaves

Felix Keneolisa Asogwa, Kenneth Obinna Okolo, Jude Ali Ibeabuchi, Celestine Obiora Ugwu, Augustine Nkemakolam Okorie

9-15 https://doi.org/10.52406/ptnm.v2i4-6.51

Vol. 2 No. 3 (2022): PTNM 2022 Third Issue

Published: 2022-07-20

Aqueous Root Extract of Strophanthus hispidus Demonstrates Antidiabetic Effect in Fructose-Streptozotocin-Induced Diabetic Rats

Muyiwa S. Fageyinbo, Abidemi J. Akindele, Joshua Falade, Esther O. Agbaje

1-8 https://doi.org/10.52406/ptnm.v2i3.40

Vol. 2 No. 2 (2022): PTNM 2022 Second Issue

Published: 2022-06-16

Mechanism and Changes Associated with Edible Camphor Induced Neurotoxicity

Anoka A. Njan

37 - 49 https://doi.org/10.52406/ptnm.v2i2.29

Ethanol Leaf Extract of Synsepalum dulcificum Schumach. & Thonn. (Sapotaceae) Induces Distortions in Renal, Hepatic and Reproductive Indices in Sprague-Dawley Rats

Abdulwasiu Adeniyi Busari, Victor Olabowale Ikumawoyi, Olawale Sultan Yusuff, Adebusayo Raimat Adeosun, Abimbola Adepeju Sowemimo, Olufunsho Awodele

50-65 https://doi.org/10.52406/ptnm.v2i2.33

Vol. 2 No. 1 (2022): PTNM 2022 First Issue

Published: 2022-01-22

Uterine Contractile Activity and Abortifacient Effect of the Aqueous Extract of Euphorbia heterophylla L. Leaves in Albino Rats

Olubunmi O. Elemo, Akinwunmi A. Akinyede, Ibrahim A. Oreagba, Viola A. Nicholas-Okpara, Jeremiah O. Unuofin

01-11 https://doi.org/10.52406/ptnm.v2i1.14

Lutein Attenuates Cyclosporin-induced Testicular Impairment in Male Rats through Modulation of Androgenic Hormones and Enzymes

Mega O. Oyovwi, Benneth Ben-Azu, Tesi P. Edesiri, Rotu R. Arientare, Victor Emojevwe, Kingsley E. Nwangwa, Kesiena E. Edje, Olusegun G. Adebayo

12-24 https://doi.org/10.52406/ptnm.v2i1.17

GC-MS Analysis, Antibacterial and Antibiofilm Activities of Extracts of Zingiber Officinalis against Staphylococcus aureus and Pseudomonas aeruginosa

Chinedu G. Ohaegbu, Anayochukwu C. Ngene, Chibuzo V. Alisigwe

25-36 https://doi.org/10.52406/ptnm.v2i1.19

Vol. 1 No. 1 (2021): PTNM 2021 First Issue

Published: 2021-09-21

Ameliorative Potential of Clerodendrum volubile Ethanol Leaf Extract on Doxorubicin-Induced Hepatorenal Toxicities in Rats

Adejuwon A. Adeneye, Olufunke E. Olorundare, Akinyele O. Akinsola, Daniel A. Sanni, James M. Ntambi, Hasan Mukhtar

1-13 https://doi.org/10.52406/ptnm.v1i1.8

Effect of Cassia fistula Hydroalcoholic Extract on Testosterone Induced Benign Prostatic Hyperplasia in Wistar Rats

Adesegun J. Kashimawo, Kemelayefa O. James, Nnabuike D. Nnamani

14-19 https://doi.org/10.52406/ptnm.v1i1.9

Effects of Aqueous Leaf Extract of Simarouba glauca DC (Simaroubaceae) on Lipoprotein Homeostasis and Oxidative Stress Biomarkers

Sammydavies E. Osagie-Eweka, Noghayin J. Orhue, Eric I. Omogbai

20 - 29 https://doi.org/10.52406/ptnm.v1i1.12